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A Cancer trial in New York City has produced a 'unprecedented' result: complete remission for all participants.

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Published By:
Peeyush Ghalot
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(Image Courtesy: - IndiaMart)

With the 100 percent successful trial of cancer medicine #dostarlimab, which entirely disappeared malignant cells from the bodies of 18 rectal cancer patients, a new era in medical research has begun. The medicine is offered under the brand name Jemperli and is an immunotherapy agent used to treat endometrial cancer, but this was the first clinical research to see if it might also be used to treat rectal cancer tumours. The patients in the study had tumours with a genetic mutation known as mismatch repair deficit (MMRd), which is found in 5-10% of rectal cancer patients. All of them had complete cancer remission and were doing quite well. Dostarlimab is a medication that contains laboratory-made molecules that function as replacement antibodies in the human body. All 18 rectal cancer patients received the same drug, and as a result of the treatment, the cancer was completely destroyed in all of them, undetectable by physical examination, endoscopy, positron emission tomography or PET scans, or magnetic resonance imaging (MRI) scans. The discoveries have caused a stir in the medical community. Dr. Alan P. Venook, a colon cancer expert at the University of California, told the news organisation that full remission in every single patient is "unheard-of." He lauded the study as a first of its kind in the globe. He went on to say that it was especially noteworthy because not all of the patients experienced serious side effects from the trial medicine. Dostarlimab was administered to the trial participants every three weeks for six months. They were all at the same stage of cancer, which had progressed locally in the rectum but had not moved to other organs.

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